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Nano Micro Lab

Nano Micro LAB lettering with schematic representation of laser ablation and processes in the plasma on a black background ©von D.Clases

In our working group, we deal with nano- and microstructures. On the one hand, we detect them as contaminants in complex environmental and biological samples, but we also use them specifically to improve analytical methods. Our focus is on atomic spectroscopy and especially on element mass spectrometry.

 

Current research topics

Biochemical reactions take place in small nano- and microscale spaces. We are developing new methods to better understand these spaces and the biological and biochemical processes that take place within them. Our aim is to better describe the physiology as well as various pathologies and to develop new concepts with which adverse changes can be recognized and averted at an early stage. For example, we investigate both element and protein biomarkers in tumor-associated microstructures, which allow important conclusions regarding cancer and possible interventions.
In addition, we functionalize nanostructures with the aim of integrating them into bioanalytical techniques in order to increase the performance of current methods.

Nano- and microparticles are ubiquitous in the environment. For the most part, they are created by natural processes, but to a lesser extent also by anthropogenic processes. While some nanostructures are believed to have played a fundamental role in the early history of the Earth and in the evolution of life, other nanostructures pose a threat to health and the environment. We are developing new techniques to detect nano- and microstructures in the environment, to clarify their origin, and to investigate their ecological impact. Mostly we are looking for metal-based nanomaterials in urban systems with significant anthropogenic impacts. In addition, we are also interested in micro- and nanoplastics and methods to better detect these "new" contaminants using mass spectrometry.

Assoz. Prof. Dr.rer.nat.
David Clases

david.clases(at)uni-graz.at

+43 316 380 - 5318
Institut für Chemie
https://chemie.uni-graz.at/de/analytische-chemie/forschung/nano-micro-lab/

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